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弥漫性大B细胞淋巴瘤NEJM音频听写

弥漫性大B细胞淋巴瘤_NEJM音频听写

DiffuseLargeB-CellLymphoma

DiffuselargeB-celllymphomainaggressivecanceraccountsforabout30%ofalllymphomas.Patientstypicallypresentwithprogressivelymphadenopathy,extranodaldisease,orbothandrequiretherapy.

Themedianageatdiagnosisisinthemid-60s;30%ofpatientsareolderthan75yearsofage.Althoughthemajorityofpatientspresentwithoutahistoryoflymphoma,diffuselargeB-celllymphomacanariseasatransformationfromanunderlyingknownoroccultlow-gradeB-celllymphoma.Epidemiologicstudiessupporta

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